Anti-inflammatory activity of hydroalcoholic extract of Helychrisum faradifani (Asteraceae) in mice

This study aimed to evaluate Helychrisum faradifani hydro alcoholic extract activity on the vascular and cellular phases of inflammation in mice. Carrageenan was injected hind-paw effect edema acetic acid 0.6 % by intra peritoneal route H. permeability. Cotton pellets imbibed with 1% carrageenan inserted skin animals investigate granuloma formation. Indomethacin at dose 10 mg/kg administered orally as positive control. The anti-inflammatory demonstrated that oral administration inhibited significantly inflammatory carrageenan-induced compared Control group paw is 0.61± 0.01 ml, versus 0.32± 0.02, 0.22± 0.15± 0.01ml respectively groups treated extract, 0.38± 0.02 for indomethacin. It also reduces permeability 34.04 ± 0.001% 67.30 0.015% control (p <0.05). weight 53.85 0.62 mg 33.32 0.3 19.95 0.38 rats 200, 400 800 Leucocytes number from 119.55 0.1in 105.1 0.1, 88.83 0.1 70.48 85.52 0.05 These results indicate inflammation.